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Lidocaine Hydrochloride is the hydrochloride salt from of lidocaine, an aminoethylamide and a prototypical member of the amide class anesthetics. Lidocaine Hydrochloride is a local anesthetic and cardiac depressant used as an antiarrhythmia agent. The actions of Lidocaine Hydrochloride are more intense and its effects more prolonged than those of Procaine but its duration of action is shorter than that of Bupivacaine or Prilocaine.
l What is the function of Lidocaine Hydrochloride?
l What should be paid attention to before taking Lidocaine Hydrochloride?
l What can Lidocaine Hydrochloride be used for?
What is the function of Lidocaine Hydrochloride?
Lidocaine Hydrochloride interacts with voltage-gated Na+ channels in the nerve cell membrane and blocks the transient increase in permeability of excitable membranes to Na+. This prevents the generation and conduction of nerve impulses and produces a reversible loss of sensation. Lidocaine Hydrochloride also exhibits class IB antiarrhythmic effects. Lidocaine Hydrochloride decreases the flow of sodium ions into myocardial tissue, especially on the Purkinje network, during phase 0 of the action potential, thereby decreasing depolarization, automaticity and excitability.
Lidocaine Hydrochloride is the drug that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. Lidocaine Hydrochloride acts on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, Lidocaine Hydrochloride can cause both sensory and motor paralysis in the innervated area. The actions of Lidocaine Hydrochloride is completely reversible. Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
Lidocaine Hydrochloride is an agent used for the treatment or prevention of cardiac arrhythmias. Lidocaine Hydrochloride may affect the polarization to repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers.
What should be paid attention to before taking Lidocaine Hydrochloride?
You should not use Lidocaine Hydrochloride if you are allergic to any type of numbing medicine.
Fatal overdoses of Lidocaine Hydrochloride have occurred when it is used without the advice of a medical doctor. However, overdose of Lidocaine Hydrochloride has also occurred in women treated with a numbing medicine before having a mammography.
Before using Lidocaine Hydrochloride, tell doctor if you have ever had liver disease, or if you take a heart rhythm medicine.
Lidocaine Hydrochloride is not expected to harm an unborn baby. Tell your doctor if you are pregnant. If you apply Lidocaine Hydrochloride to your chest, avoid areas that may come into contact with the baby's mouth.
Lidocaine Hydrochloride can cause side effects that may impair your thinking or reactions. Unless absolutely necessary, do not drive after receiving Lidocaine Hydrochloride. Avoid eating or chewing within 1 hour after Lidocaine Hydrochloride is used to numb your mouth or throat. You may have trouble swallowing which could lead to choking. You may also accidentally bite the inside of your mouth if you are still numb an hour after treatment with Lidocaine Hydrochloride.
What can Lidocaine Hydrochloride be used for?
Lidocaine Hydrochloride is suitable for acute ventricular arrhythmias caused by acute myocardial infarction, surgery, digitalis poisoning and cardiac catheterization, including ventricular premature beats, ventricular tachycardia and ventricular fibrillation. Lidocaine Hydrochloride is also used in status epilepticus for those who are ineffective with other anticonvulsants and local or intraspinal anesthesia. Lidocaine Hydrochloride can also relieve tinnitus.
Lidocaine Hydrochloride can mainly be used for peripheral block anesthesia, infiltration anesthesia, surface anesthesia and epidural anesthesia. Lidocaine Hydrochloride can also be used to treat premature ventricular contractions after acute myocardial infarction, digitalis poisoning, cardiac surgery, and ventricular arrhythmia caused by cardiac catheterization.
l Lidocaine Hydrochloride gel can be used for those who need local anesthesia for examination and treatment through the urethra.
l Lidocaine Hydrochloride patch can be used to relief of post-herpetic neuralgia.
l Lidocaine Hydrochloride glue is often used as surface anesthesia, including mucosal anesthesia during thoracoscopy or abdominal surgery.
l Lidocaine Hydrochloride aerosol are used as local anesthesia of skin and mucous membranes, such as minor oral and nasal mucosal surgery, dental extraction surgery, abscess incision surgery.
l Lidocaine Hydrochloride mouthwash is to relieve pain caused by irritation or inflammation of the oral cavity and pharynx mucosa; surface anesthesia for bronchoscopy and esophagoscopy; upper gastrointestinal pain.
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