What are the properties and effects of Pregabalin?

Pregabalin capsules, oral solution (liquid), and extended-release (long-acting) tablets are used for the relief of neuropathic pain (pain caused by nerve damage) that may occur in the arms, hands, fingers, legs, feet, or toes suffering from diabetes and post-herpetic neuralgia. Before using Pregabalin medication, we should understand its properties and effects. Here is the content list.

Here is the content list:

l Properties

l Efficacy

Properties

Physical and chemical properties

Pregabalin is a white or almost white crystalline powder in appearance. It has a density of 0.997 g/cm3, a melting point of 194-196ºC, a boiling point of 274ºC at 760 mmHg, a flashpoint of 119.5ºC, a refractive index of 1.464 and a vapor pressure of 0.00153 mmHg at 25°C. It is soluble in water as well as basic and acidic aqueous solutions. pH 7.4 has a logarithmic partition coefficient (octanol/0.05 M phosphate buffer) of - 1.35.

Addictive properties

Although it can help many people, this drug can sometimes lead to addiction. This risk may be higher if you have a substance use disorder (e.g., overuse or addiction to drugs/alcohol). Therefore, this medication needs to be taken as prescribed to reduce the risk of addiction. Please consult your doctor or pharmacist for more details.

Allergic

Taking Pregabalin may cause allergic reactions in some people. In severe cases, it may even cause life-threatening allergic reactions such as swelling of the face, mouth, lips, gums, tongue, throat, or neck, difficulty breathing, rash, hives (raised bumps), or blisters. If you experience any of these symptoms, call your healthcare provider immediately.

You should not stop taking it suddenly

It is important to note that you should not stop taking Pregabalin without consulting your doctor. Some conditions may become worse when this medicine is suddenly stopped. For example, you may experience difficulty sleeping, nausea, headache, and diarrhea. To prevent these symptoms from occurring when you stop treatment with this medicine, your doctor may gradually reduce your dose. Always remember to report any new or worsening symptoms immediately.

Efficacy

Pregabalin is a commonly used drug in neurology with anti-epileptic, sedative, and anti-anxiety effects. The mechanism of the antiepileptic action of Pregabalin is not yet clear. In experimental animal studies, Pregabalin has shown anticonvulsant effects in various types of animal models of epilepsy, with its animal model being several times more active than that of gabapentin. Clinically, Pregabalin is generally used for the following disorders. Firstly, to improve neuralgia, including peripheral neuralgia due to diabetic peripheral neuropathy, postherpetic neuralgia, sciatica, trigeminal neuralgia, post-operative toothache, and arthritis. Secondly, anti-epileptic, for the adjunctive treatment of partial seizures. The third is anti-anxiety, used as an adjunctive treatment for anxiety disorders, social phobia, etc.

Mulei (Wuhan) New Material Technology Co. Ltd has many years of experience in the production of Pregabalin. Over the years we have always been careful in the development of our drugs, which has led to the production of drugs known for their therapeutic efficiency. Log on to https://www.whmulei.com/ and you can learn more about our company.