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Phenacetin is a synthetic, white crystalline solid that is slightly soluble in water and benzene, while soluble in acetone and easy to soluble in pyrimidine. Phenacetin is used in research as the preferred marker for detecting CYP1A2-based inhibition potential in vitro. The ingestion of Phenacetin can result in a bluish discoloration of the skin due to a lack of oxygen in the blood, dizziness and respiratory depression. Phenacetin is reasonably anticipated to be a human carcinogen. Phenacetin is an odorless, white crystalline solid with a lightly bitter taste, which is used as an analgesic medicine.
Does Phenacetin belong to amino compound?
How to deal with the leakage of Phenacetin?
How to store Phenacetin?
Amino compounds contain amino groups. Amino-NH2 is a group formed by removing a hydrogen atom from an ammonia molecule. If a group that RNH- or R2N- is formed by removing a hydrogen atom from the amino group of a certain amine RNH2, R2NH, it is called a certain amino group, such as methylamino and diethylamino. Phenylamino are polar and basic groups. Inorganic compounds are amides. There are amines, amino acids, amides and so on in organics.
Acetaminophen is a metabolite of Phenacetin in the body, which is a type of amino compounds. The antipyretic and analgesic effect of amino compound is similar to that of Aspirin so that Phenacetin can antipyretic and analgesia.
Amide compound of Phenacetin is an aniline antipyretic and analgesic drug. Acetaminophen is a metabolite of Phenacetin in the body, which is one type of amide compound. The antipyretic and analgesic effect of amide compound is similar to that of Aspirin.
The anti-inflammatory and anti-rheumatic effects of amide compound of Phenacetin are very weak or even, have no curative effect. Amide compound of Phenacetin has no irritation to the gastrointestinal tract, as well as not causing coagulation disorders.
Protective measures, protective equipment and emergency procedures for workers:
It is recommended that emergency personnel wear air-contained breathing apparatus, anti-static clothing, and rubber and oil-resistant gloves.
Do not touch or cross Phenacetin.
All equipment used during operation should be grounded.
Cut off the source of leakage Phenacetin as much as possible.
Eliminate all ignition sources.
According to the area affected by liquid flow, steam or dust diffusion of Phenacetin, the warning zone shall be delineated. Irrelevant personnel shall be evacuated from the crosswind and upwind direction to the safe area.
Environmental protection measures: Contain leakage Phenacetin to avoid environmental pollution. Prevent leaks from entering sewers, surface water and groundwater.
The containment and removal methods of the leaked Phenacetin and the disposal materials used:
As for small amount of leakage Phenacetin, we should collect the leakage Phenacetin in a sealable container as much as possible. Absorb with sand, activated carbon or other inert materials and transfer to a safe place. Do not flush Phenacetin into the sewer.
With regard to a large number of leakage Phenacetin, we should construct a dike or dig a pit for storage. Close the drainage pipe. Cover with foam to prevent Phenacetin from evaporating. Use explosion-proof pump to transfer to tank truck or special collector, recycle or transport to waste disposal site for disposal.
Phenacetin should be stored in a cool, ventilated warehouse. The storage temperature should not exceed 37°C. The warehouse to store Phenacetin must be equipped with lightning protection equipment. The warehouse should use explosion-proof lighting and ventilation settings. The exhaust system of the warehouse where stores Phenacetin should be equipped with a grounding device to remove static electricity. The storage area of Phenacetin should be equipped with leakage emergency treatment equipment and suitable storage materials. It is forbidden to use equipment and tools that are prone to sparks.
Phenacetin should be stored separately from oxidants and edible chemicals, and should not be mixed. Phenacetin should be kept in the container tightly closed, as well as keeping away from fire and heat sources.
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