How to understand Pregabalin?

Pregabalin is an anti-epileptic drug, also called an anticonvulsant. Pregabalin may be used in the treatment of some seizure disorders and also for the control of nerve pain. Research has shown that Pregabalin binds strongly to a specific site on voltage-gated calcium channels, which is thought to be the mechanism for its nerve-pain-relieving and anti-seizure properties.

Who should take Pregabalin with caution?

How does Pregabalin work?

Which drugs can cause interactions with Pregabalin?

Who should take Pregabalin with caution?

If you have kidney problems or a history of kidney disease, you may not be able to clear Pregabalin from your body well. This may increase the levels of Pregabalin and cause more side effects.

For people with heart problems, ask your doctor whether Pregabalin is safe for you if you have heart problems, such as moderate to severe heart failure. Pregabalin can make your condition worse. Symptoms of worsening heart problems can include swelling in your arms, legs, or feet, weight gain, and fluid retention in your body.

For people with depression or mental health issues, Pregabalin may increase your risk of suicidal thoughts and behaviors. You and your family should watch for new or worsened depression, unusual changes in your mood or behavior, or thoughts of harming yourself.

Let your doctor know if you have misused prescription or street drugs or alcohol in the past. Pregabalin is a controlled substance and its use can lead to misuse.

Talk to your doctor if you’re pregnant or planning to become pregnant. Pregabalin should only be used if the potential benefit justifies the potential risk. It has shown that high doses of Pregabalin increased the risk of negative effects to the fetus.

For women who are breastfeeding, Pregabalin passes into breast milk in small amounts. Therefore, Pregabalin may cause side effects in a child who is breastfed.

For men with plans to father a child, it has shown that Pregabalin caused sperm to change and made male animals less fertile. Also, birth defects were seen in the babies of male animals who were treated with Pregabalin.

How does Pregabalin work?

Pregabalin belongs to a class of drugs called anticonvulsants, which is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. It isn’t known exactly how Pregabalin works. It’s believed to work by calming the damaged or overactive nerves in your body that may cause pain or seizures.

Pregabalin works by slowing down impulses in the brain that cause seizures. Pregabalin also affects chemicals in the brain that send pain signals across the nervous system.

Pregabalin is a new type of gamma-aminobutyric acid receptor agonist, which can block voltage-dependent calcium channels and reduce the release of neurotransmitters. Pregabalin is mainly used for the treatment of peripheral neuralgia and adjuvant treatment of localized Seizures parts.

Use Pregabalin as ordered by your doctor, reading all information given to you. Follow all instructions closely. Take Pregabalin with or without food. Keep taking Pregabalin as you have been told by your doctor or other health care provider, even if you feel well. Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses of Pregabalin at the same time or extra doses.

Which drugs can cause interactions with Pregabalin?

Pregabalin can interact with other medications, such as vitamins, or herbs you may be taking. An interaction is when a substance changes the way Pregabalin works, which can be harmful or prevent Pregabalin from working well.

To help avoid interactions, doctor should manage all of your medications carefully. Be sure to tell doctor about all medications. To find out how Pregabalin might interact with something else you’re taking, talk to your doctor or pharmacist.

l Taking Pregabalin with certain medications may cause more side effects.

l Diabetes drugs, such as rosiglitazone and pioglitazone. Taking these drugs with Pregabalin may cause weight gain or swelling of your hands or feet. If you have heart problems, taking these drugs together with Pregabalin can increase your risk of heart failure.

l Narcotic pain drugs, such as oxycodone. Taking these drugs with Pregabalin may cause dizziness and sleepiness.

l Tranquilizers or drugs for anxiety, such as lorazepam. Taking these drugs with Pregabalin may cause dizziness and sleepiness.

l Blood pressure drugs, such as captopril, enalapril, or lisinopril. Taking these drugs with Pregabalin may cause swelling and hives.

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