How to understand Biochemical Enzymes and coenzymes?

Since the end of the 19th century, German biologist Bischner proved that yeast cell-free extract can ferment sugar to produce alcohol, and first proposed the name of enzymes, humans have found and identified more than 3,000 enzymes. As a kind of catalyst, the enzyme has been widely used in various fields of the light industry. In recent decades, with the rapid development of enzyme engineering, enzymes in biological engineering, biological sensors, environmental protection, medicine, and other aspects of the application are also growing, to say the enzyme has become an indispensable part of the national economy, in real life, people's food, clothing, shelter, line, and other aspects of the new technology almost cannot leave the enzyme. The following will introduce you to the related knowledge of biochemical enzymes and coenzymes.

Here is the content list:

l What are coenzymes?

l What is a biochemical enzyme?

l What is the relationship between biochemical enzymes and coenzymes?

What are coenzymes?

Coenzymes are small organic molecules that can transfer chemical groups from one enzyme to another. They are loosely bound to enzymes and are necessary for the activity of specific enzymes. There are many vitamins and their derivatives, such as thiamine and folic acid, which are all coenzymes. These compounds cannot be synthesized by the human body and must be supplemented through diet.

Common coenzymes are thiamine, nicotinamide, coenzyme I (NAD), riboflavin, pyridoxal, and its derivatives.

In the cell, the reacted coenzyme can be regenerated to maintain its intracellular concentration at a stable level. For example, NADPH can be regenerated by the pentose phosphate pathway and S-adenosylmethionine under the action of methionine adenyl transferase. Since the regeneration of the coenzyme is necessary to maintain the stability of the enzyme reaction system, the coenzyme regeneration system has obtained a large number of laboratory and industrial applications. (Coenzyme cannot be called a catalyst).

What is a biochemical enzyme?

Biochemical enzymes can be divided into biological enzymes and chemical enzymes. Chemical enzymes are mainly used in the washing industry, baking food, and brewing industry in daily life. Nearly a thousand enzymes have been found in the human body. Lack or insufficiency of enzymes will affect a certain biochemical reaction, metabolic disorders, and maybe manifested as diseases. For example, a form of albinism, in which the skin and hair are white. Because lack of tyrosinase inside the body namely, as a result, does not have melanin to form be caused by. So by measuring the level of enzymes in the body can help to diagnose the disease. Some enzymes can also be used to treat diseases.

Enzymes are catalytic organic compounds produced by living cells, mostly proteins and a small amount of RNA. The manufacturing and application of biological enzymes are gradually expanding, the application of biological enzymes in the textile industry is becoming mature, from the past mainly used in the designing of cotton fabric and silk degumming, to now in the textile dyeing and finishing of various fields of wide application reflects the superiority of biological enzymes in the dyeing and finishing industry. An important breakthrough was made in the field of human skincare in 2016, and the enzyme has entered the clinical application stage.

What is the relationship between biochemical enzymes and coenzymes?

In addition to the protein part, some biochemical enzymes also contain some inorganic or organic components that are directly related to their functions. These components are collectively referred to as the cofactors of biochemical enzymes. If these components are lacking, the enzymes will not show activity. Although different from the substrate of the enzyme, the coenzyme acts similarly to the substrate, binding, separating, and recycling with the enzyme during the enzymatic reaction. Coenzyme dosage can be determined by treating them as substrates. For example, the coenzyme in lactate dehydrogenase is calculated according to the double substrate kinetics equation. Many enzymes contain both metal cofactors and coenzymes. Many coenzymes are derivatives of or vitamins.

Mulei (Wuhan) New Material Technology Co. Ltd., has developed a variety of biochemical enzymes and coenzymes and conducted a lot of tests before leaving the factory to ensure quality. These biochemical enzymes and coenzymes not only have a large exhaust capacity but also have strong endurance. If you are in the biochemical enzymes and coenzymes business, you can consider using our cost-effective products.